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Cannabis for the Treatment of Cancer - Scientific Details in Report
The 182 page report titled "Cannabis for the Treatment of Cancer: The Anticancer Activity of Phytocannabinoids and Endocannabinoids" by Justin Kander and edited by Dennis Hill reveal detailed descriptions of studies where cannabis stopped cancer cells from surviving, spreading and metastasizing. Included are also personal testimonies of patients that have used cannabis to treat their cancer. The U.S. government chooses to ignore this critical information and instead continues to publically vilify cannabis, thereby denying cancer patients this potentially life saving medicine.
Here's some definitions to help with clarity;
phytocannabinoid = cannabinoid created by and found in vegetative plants such as Cannabis sativa.
endogenous cannabinoid (endocannabinoid) = cannabinoid created and found internally in human/animal body, part of endocannabinoid system.
Summary of intro to report;
There are millions of cancer deaths worldwide every year despite access to conventional treatments such as chemotherapy and radiation. However, an accumulation of research has demonstrated that phytocannabinoids from whole plant cannabis can actually reduce cancer cells in the body while leaving healthy cells intact. It is uncertain whether certain types of cancers will respond to various cannabinoids, though it is generally true that cannabis has an anti-cancer effect in addition to combating nausea from chemotherapy.
The human endocannabinoid system (ECS) is a network of cannabinoid receptors, endogenous cannabinoids and enzymes that work together to maintain homeostasis or balance in the body as environmental conditions change. An example is that the ECS will release endogenous cannabinoids following a head injury and resulting brain trauma to prevent damage to vital cells. It is now becoming evident that the ECS protects against cancer also, and that additional phytocannabinoids from cannabis assist the ECS in fighting cancer.
Apoptosis (programmed cell death) is the most powerful way that both endogenous and phytocannabinoids protect against cancer. Most cells will automatically go through apoptosis once they become old and damaged, though cancer cells grow abnormally and do not. The phtyocannabinoids from cannabis plants cause the cancer cells to turn on their apoptosis programming, thus killing the cancer cells in the process. Healthy cells remain undisturbed and functional.
In addition to causing cancer cells to self-destruct through apoptosis, cannabis also stops tumors from forming their own blood vessels (anti-angiogenic), slows cancer cell reproduction (anti-prolific), and stops cancer from spreading within local tissues (anti-invasive) and moving to other tissues (anti-metastatic).
To learn more and see detailed studies of cannabis and a particular type of cancer, visit this link;
https://www.dropbox.com/s/rk0vbpcjz3pbehe/Cannabis%20and%20Cancer.pdf?dl=0
Commentary from Green Liberty Party - U.S. Presidential candidate Mark Paul Miller;
This is great news for anyone with cancer and their friends and family, though the question remains; Why isn't this potentially life saving information about cannabis killing cancer more widely known?
Perhaps the U.S. DEA wishes to maintain their illogical claims "cannabis is dangerous and has no medical benefit" because they are unwilling to admit to error? Is the media playing the DEA's lapdog?
Are the government forces of "protection" not able to realize that they made a mistake when it comes to cannabis? It could be true that in their overzealous standards of drug enforcement against cannabis the DEA has prevented millions of people from accessing a safe plant medicine against deadly cancer! In net effect the DEA prohibition of cannabis has resulted in many needless deaths and suffering from cancer. If the DEA cannot be bothered to read a new science report showing cannabis kills cancer, maybe a class action lawsuit charging them with negligent homicide of cancer patients by preventing access to a known safe medicine will send a stronger message.
What about pharmaceutical corporations being threatened by cannabis becoming the preferred treatment for cancer instead of deadly chemotherapy and damaging radiation? Surely their profits will decrease over the next decade as cannabis treatments for cancer prove successful at a greater rate. That would be reason enough for pharma to threaten media networks with pulling their commercials should the newscasters dare expose this research.
Either reason could be true, so it is up to the independent media once again to spread the truth and cover under-reported stories.
The GLP position of Presidential candidate Mark Paul Miller is for complete legalization (taxation + regulation) of cannabis for both recreational and medical purposes and that ALL verified cancer patients are aware of and have access to free (government grown) cannabis for treatment of their cancer if they choose to.
phytocannabinoid = cannabinoid created by and found in vegetative plants such as Cannabis sativa.
endogenous cannabinoid (endocannabinoid) = cannabinoid created and found internally in human/animal body, part of endocannabinoid system.
Summary of intro to report;
There are millions of cancer deaths worldwide every year despite access to conventional treatments such as chemotherapy and radiation. However, an accumulation of research has demonstrated that phytocannabinoids from whole plant cannabis can actually reduce cancer cells in the body while leaving healthy cells intact. It is uncertain whether certain types of cancers will respond to various cannabinoids, though it is generally true that cannabis has an anti-cancer effect in addition to combating nausea from chemotherapy.
The human endocannabinoid system (ECS) is a network of cannabinoid receptors, endogenous cannabinoids and enzymes that work together to maintain homeostasis or balance in the body as environmental conditions change. An example is that the ECS will release endogenous cannabinoids following a head injury and resulting brain trauma to prevent damage to vital cells. It is now becoming evident that the ECS protects against cancer also, and that additional phytocannabinoids from cannabis assist the ECS in fighting cancer.
Apoptosis (programmed cell death) is the most powerful way that both endogenous and phytocannabinoids protect against cancer. Most cells will automatically go through apoptosis once they become old and damaged, though cancer cells grow abnormally and do not. The phtyocannabinoids from cannabis plants cause the cancer cells to turn on their apoptosis programming, thus killing the cancer cells in the process. Healthy cells remain undisturbed and functional.
In addition to causing cancer cells to self-destruct through apoptosis, cannabis also stops tumors from forming their own blood vessels (anti-angiogenic), slows cancer cell reproduction (anti-prolific), and stops cancer from spreading within local tissues (anti-invasive) and moving to other tissues (anti-metastatic).
To learn more and see detailed studies of cannabis and a particular type of cancer, visit this link;
https://www.dropbox.com/s/rk0vbpcjz3pbehe/Cannabis%20and%20Cancer.pdf?dl=0
Commentary from Green Liberty Party - U.S. Presidential candidate Mark Paul Miller;
This is great news for anyone with cancer and their friends and family, though the question remains; Why isn't this potentially life saving information about cannabis killing cancer more widely known?
Perhaps the U.S. DEA wishes to maintain their illogical claims "cannabis is dangerous and has no medical benefit" because they are unwilling to admit to error? Is the media playing the DEA's lapdog?
Are the government forces of "protection" not able to realize that they made a mistake when it comes to cannabis? It could be true that in their overzealous standards of drug enforcement against cannabis the DEA has prevented millions of people from accessing a safe plant medicine against deadly cancer! In net effect the DEA prohibition of cannabis has resulted in many needless deaths and suffering from cancer. If the DEA cannot be bothered to read a new science report showing cannabis kills cancer, maybe a class action lawsuit charging them with negligent homicide of cancer patients by preventing access to a known safe medicine will send a stronger message.
What about pharmaceutical corporations being threatened by cannabis becoming the preferred treatment for cancer instead of deadly chemotherapy and damaging radiation? Surely their profits will decrease over the next decade as cannabis treatments for cancer prove successful at a greater rate. That would be reason enough for pharma to threaten media networks with pulling their commercials should the newscasters dare expose this research.
Either reason could be true, so it is up to the independent media once again to spread the truth and cover under-reported stories.
The GLP position of Presidential candidate Mark Paul Miller is for complete legalization (taxation + regulation) of cannabis for both recreational and medical purposes and that ALL verified cancer patients are aware of and have access to free (government grown) cannabis for treatment of their cancer if they choose to.
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Thanks Justin for the great report! My intro to this info was from an employee at a dispensary who told me about the YouTube video with Dr. Christina Sanchez "cannabis kills cancer while leaving healthy cells intact". My mom had already begun chemo for several years before this info was known to me. Had we found out sooner maybe she would have had a better outcome. She was able to try some cannabis at the very end and her oncologist said that she did "better than expected", so maybe it helped a bit. Unfortunately she lost her life to a simple infection following a year of intense chemo.
This knowledge about cannabis killing cancer needs to be made available to the public, yet the FDA/DEA keeps trying to sweep it under the rug.
The differences in THC and CBD usage should be mentioned. The report states that THC is more effective against cancer following a brief period of abstinence before resuming treatment. Two days of no THC intake and then two days of using THC is the pattern for killing cancer cells. If THC is taken everyday the effectiveness against cancer cells wears off. CBD can be used daily, but THC should have "time off" to be more effective. That is the general idea, though the details could vary from person to person.
This knowledge about cannabis killing cancer needs to be made available to the public, yet the FDA/DEA keeps trying to sweep it under the rug.
The differences in THC and CBD usage should be mentioned. The report states that THC is more effective against cancer following a brief period of abstinence before resuming treatment. Two days of no THC intake and then two days of using THC is the pattern for killing cancer cells. If THC is taken everyday the effectiveness against cancer cells wears off. CBD can be used daily, but THC should have "time off" to be more effective. That is the general idea, though the details could vary from person to person.
pg. 40; "An interesting observation was the benefit of a 'recovery phase' for increasing cytotoxicity. The researchers observed that prolonged cannabis treatment had a cytostatic effect rather than cytotoxic. However, by stopping cannabis treatment after several days of administration, the cell cycle resumes and the [cancer] cells die."
Today is a sad day as everyone says goodbye to Aretha Franklin and Sen. John McCain, both lost to cancer. Even though many anti-war activists disliked the Senator's pro-war foreign policy, at least he stood up to Trump's bullying him and other POWs. It is unknown if either of them knew or tried cannabis to help kill cancer cells alongside chemo/radiation.
How do you advise people to go about using cannabis for killing cancer if the FDA doesn't want to hear about it and try to help humans to access it and research the most effective dosages and timings? Mark Paul Miller of the Green Liberty Party wants to share this info, but he is no doctor! Giving medical advice isn't a good idea, this is just sharing knowledge that links to someone else's research. They've had over ten years since Dr.Christina Sanchez of Complutense University in Madrid discovered that cannabis kills cancer cells. Why didn't Aretha Franklin and Sen. McCain have hospitals and doctors that would try cannabis either with or separate from chemo/radiation/surgery?
Note on the above comment with the theme, "2 days break from THC with CBD everyday."
This requires explanation of the words "cytotoxic" and "cytostatic" in the quote from the report;
cytotoxic kills the cancer cells while cytostatic is neutral towards the cancer cells, it doesn't help or harm them. So they say in that one report (based on leukemia, it doesn't test for other cancers) when claiming the effectiveness basically wears off if the THC use is continuous. Does that mean 48 hours (2 days) or 24 hours or 12? How did I come up with 48 hours?
The tolerance effect of THC in cannabis is noticed as it wears off and leaves the body. According to their leukemia study, if THC remains in the body all the time from continuous usage, it begins to lose effectiveness and becomes cytostatic. However, a break consisting of the average time (about 24-48 hours) it takes for the THC to leave the body then increases effectiveness, making it cytotoxic to cancer cells once again.
If this is true, then the same effect is noticed by people who feel it's mental effects wear off after continuous usage, the tolerance is the same way with the cancer. The longer duration between THC consumption the stronger it will be against the cancer cells. By waiting at least 48 hours between THC consumption times it will be that much more effective, according to their leukemia study. That isn't advice, just theory. Just because it works that way for leukemia in their report doesn't mean it effects other cancers the same way, though it could. Science is mostly guesswork until someone else does another study for a different cancer and then see if they come up with the same results. Until then it is all speculation. Anyone who tries cannabis to kill cancer is forging new ground in medical history, there is no real guidance besides interpreting these reports as best as one is able to. Nobody really knows for sure, I am just guessing. If a reader wants to try cannabis to kill their cancer, they are on their own.
CBD can be consumed 24/7 if needed for nausea and general well being, but THC should be taken in 24/48 hour cycles, IF this applies to other cancers besides leukemia. Though in theory this would make sense as some cancers can develop resistance with continuous exposure and the THC will not wear out due to tolerance of the cancer or if it is loss of effect.
Further research is needed and there are many lives needlessly gone prematurely from cancer simply because the DEA and FDA don't want to read a science report and take it seriously!
Today I am doubly sad because I don't even know if either Aretha Franklin or Sen. McCain were made aware of the cannabis kill's cancer report's existence. Even if the FDA hasn't approved it, people should have the right to know it is a real peer reviewed science report. The corporate media still hasn't covered it, other than a few here and there. Thanks indymedia editors and contributors for publishing this and maintaining a free speech media website.
Some 2018 updates on cannabis killing cancer cells from Scientific American;
"We’re not there yet, but while the available data are limited, research that has been conducted around antitumor effects of cannabinoids so far shows great promise. The International Journal of Oncology published a study last year, for example, indicating that cannabinoids successfully kill cancer cells, and the benefits increase when combined with chemotherapy. An early preclinical study we recently conducted also found that cancer cells derived from patient blood samples were differentially sensitive to the two main active compounds in cannabis—tetrahydrocannabinol (THC) and tetrahydrocannabinolic acid (THCA). "
https://blogs.scientificamerican.com/observations/cannabis-versus-cancer/
How do you advise people to go about using cannabis for killing cancer if the FDA doesn't want to hear about it and try to help humans to access it and research the most effective dosages and timings? Mark Paul Miller of the Green Liberty Party wants to share this info, but he is no doctor! Giving medical advice isn't a good idea, this is just sharing knowledge that links to someone else's research. They've had over ten years since Dr.Christina Sanchez of Complutense University in Madrid discovered that cannabis kills cancer cells. Why didn't Aretha Franklin and Sen. McCain have hospitals and doctors that would try cannabis either with or separate from chemo/radiation/surgery?
Note on the above comment with the theme, "2 days break from THC with CBD everyday."
This requires explanation of the words "cytotoxic" and "cytostatic" in the quote from the report;
cytotoxic kills the cancer cells while cytostatic is neutral towards the cancer cells, it doesn't help or harm them. So they say in that one report (based on leukemia, it doesn't test for other cancers) when claiming the effectiveness basically wears off if the THC use is continuous. Does that mean 48 hours (2 days) or 24 hours or 12? How did I come up with 48 hours?
The tolerance effect of THC in cannabis is noticed as it wears off and leaves the body. According to their leukemia study, if THC remains in the body all the time from continuous usage, it begins to lose effectiveness and becomes cytostatic. However, a break consisting of the average time (about 24-48 hours) it takes for the THC to leave the body then increases effectiveness, making it cytotoxic to cancer cells once again.
If this is true, then the same effect is noticed by people who feel it's mental effects wear off after continuous usage, the tolerance is the same way with the cancer. The longer duration between THC consumption the stronger it will be against the cancer cells. By waiting at least 48 hours between THC consumption times it will be that much more effective, according to their leukemia study. That isn't advice, just theory. Just because it works that way for leukemia in their report doesn't mean it effects other cancers the same way, though it could. Science is mostly guesswork until someone else does another study for a different cancer and then see if they come up with the same results. Until then it is all speculation. Anyone who tries cannabis to kill cancer is forging new ground in medical history, there is no real guidance besides interpreting these reports as best as one is able to. Nobody really knows for sure, I am just guessing. If a reader wants to try cannabis to kill their cancer, they are on their own.
CBD can be consumed 24/7 if needed for nausea and general well being, but THC should be taken in 24/48 hour cycles, IF this applies to other cancers besides leukemia. Though in theory this would make sense as some cancers can develop resistance with continuous exposure and the THC will not wear out due to tolerance of the cancer or if it is loss of effect.
Further research is needed and there are many lives needlessly gone prematurely from cancer simply because the DEA and FDA don't want to read a science report and take it seriously!
Today I am doubly sad because I don't even know if either Aretha Franklin or Sen. McCain were made aware of the cannabis kill's cancer report's existence. Even if the FDA hasn't approved it, people should have the right to know it is a real peer reviewed science report. The corporate media still hasn't covered it, other than a few here and there. Thanks indymedia editors and contributors for publishing this and maintaining a free speech media website.
Some 2018 updates on cannabis killing cancer cells from Scientific American;
"We’re not there yet, but while the available data are limited, research that has been conducted around antitumor effects of cannabinoids so far shows great promise. The International Journal of Oncology published a study last year, for example, indicating that cannabinoids successfully kill cancer cells, and the benefits increase when combined with chemotherapy. An early preclinical study we recently conducted also found that cancer cells derived from patient blood samples were differentially sensitive to the two main active compounds in cannabis—tetrahydrocannabinol (THC) and tetrahydrocannabinolic acid (THCA). "
https://blogs.scientificamerican.com/observations/cannabis-versus-cancer/
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